Description
Ceftazidime & Tazobactam Injection 1.125 is a potent combination of various antibiotics widely used to treat severe bacterial infections. Ceftazidime, a third-generation cephalosporin, works by inhibiting bacterial cell wall synthesis, while Tazobactam, a β-lactamase inhibitor, enhances its effectiveness against resistant bacteria.
This injectable formulation is commonly prescribed for complicated urinary tract infections, respiratory tract infections, intra-abdominal infections, and sepsis caused by susceptible microorganisms. Its synergistic action ensures rapid and effective bacterial eradication, making it a reliable choice in hospital and clinical settings. Proper administration under medical supervision is essential to achieve optimal therapeutic outcomes. Call Fortune Labs for more such information and more products available
Constituents of Ceftazidime & Tazobactam Injection 1.125
Ceftazidime (1000 mg / 1 g): A third-generation cephalosporin antibiotic that kills bacteria by preventing the formation of their cell walls.
Tazobactam (125 mg): A beta-lactamase inhibitor that does not kill bacteria directly but protects Ceftazidime from being destroyed by bacterial enzymes (beta-lactamases), thereby overcoming antibiotic resistance.
Uses of Ceftazidime & Tazobactam Injection 1.125MG
Respiratory Tract Infections: Including severe pneumonia, hospital-acquired pneumonia, and lung infections in patients with cystic fibrosis.
Urinary Tract Infections (UTI): Effective for complicated or multi-drug resistant UTIs and kidney infections like pyelonephritis.
Abdominal Infections: Used to treat peritonitis, appendicitis, and other intra-abdominal infections.
Skin and Soft Tissue Infections: Treats cellulitis, abscesses, infected burns, and diabetic foot infections.
Brain and Spinal Cord Infections: Specifically used for bacterial meningitis and brain abscesses.
Bloodstream Infections: Effective for septicaemia (blood poisoning) and bacteremia.
Bone and Joint Infections: Including osteomyelitis and septic arthritis.
Surgical Prophylaxis: Given to prevent infections during or after certain surgeries, such as prostate surgery.
Febrile Neutropenia: Manages infections in patients with low white blood cell counts who develop a fever.
Administration: It must be administered only by a healthcare professional as an intravenous (IV) or intramuscular (IM) injection.
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- Fortune Labs, with all the latest molecules and continuously progressing under the table guidance of our Managing Experts.
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Precautions for Using Ceftazidime & Tazobactam Injection 1.125
Allergic Reactions: Do not use if you have a known history of severe allergy to cephalosporins, penicillins, or other beta-lactam antibiotics. Seek immediate emergency help if you experience a rash, swelling (face/throat), or difficulty breathing.
Renal & Hepatic Impairment: Extreme caution is required if you have kidney disease, as the drug is primarily cleared through the kidneys and may require dose adjustments to avoid toxicity (e.g., seizures or confusion). Inform your doctor if you have a history of liver disease.
Gastrointestinal Issues: This medication can cause severe diarrhea (Clostridium difficile-associated diarrhea). Contact your doctor immediately if you develop severe, watery, or bloody stools even weeks after completing treatment.
Pregnancy & Breastfeeding: Consult your doctor before use. It is generally avoided in pregnancy unless necessary. Low levels may pass into breast milk; monitor infants for diarrhea, rash, or yeast infections.
Frequently Asked Questions
What is Ceftazidime & Tazobactam Injection 1.125 g?
It is a fixed-dose combination of Ceftazidime (1 g) and Tazobactam (125 mg), where Ceftazidime is a broad-spectrum cephalosporin antibiotic, and Tazobactam is a β-lactamase inhibitor that enhances its activity against resistant bacteria.
How does this combination work?
Ceftazidime inhibits bacterial cell wall synthesis, leading to bacterial death, while Tazobactam prevents β-lactamase enzymes from degrading the antibiotic, thereby extending its spectrum and reducing resistance.
What infections does this injection treat?
It is indicated for serious bacterial infections such as lower respiratory tract infections, complicated urinary tract infections, intra-abdominal infections, skin and soft tissue infections, septicemia, and other hospital-acquired infections.
How is the injection administered?
It is administered as an intravenous (IV) infusion or intramuscular (IM) injection by a qualified healthcare professional.
How often should it be given?
Dosage and frequency depend on the severity and type of infection and patient condition; follow the prescribing clinician’s instructions. Healthcare providers typically adjust dosing based on clinical response and patient factors.
Can the injection be self-administered?
No. A healthcare professional must administer it in a hospital or clinical setting.
How soon does it work?
Initial improvement is commonly seen within a few days of starting therapy, but the full course prescribed should always be completed
