Description
Ceftriaxone & Sulbactam for Injection 375 mg is a combination antibiotic formulation designed for the effective management of a broad range of bacterial infections. It pairs Ceftriaxone, a third-generation cephalosporin antibiotic known for its broad-spectrum bactericidal activity, with Sulbactam, a beta-lactamase inhibitor that protects Ceftriaxone from enzymatic degradation by certain resistant bacteria.
This synergistic pairing enhances the overall antibacterial efficacy, making the product suitable for treating infections caused by both gram-positive and gram-negative organisms. The injection is intended for parenteral administration by a qualified healthcare professional and is typically used in clinical settings to address moderate to serious bacterial infections under medical supervision. Call Fortune Labs for more such information and products for PCD Distributorship.
Key Components of Ceftriaxone & Sulbactam for Injection 375MG
Active Components & Dosage
In a 375 mg vial, the active ingredients are typically distributed in a 2:1 ratio:
Ceftriaxone (250 mg): A third-generation cephalosporin antibiotic.
Sulbactam (125 mg): A beta-lactamase inhibitor.
Pharmacological Mechanisms
Ceftriaxone: Works by inhibiting bacterial cell wall synthesis. It binds to penicillin-binding proteins (PBPs), disrupting the creation of the peptidoglycan layer, which leads to cell lysis and bacterial death.
Sulbactam: Prevents the destruction of ceftriaxone by certain bacteria that produce beta-lactamase enzymes. By neutralizing these enzymes, sulbactam expands the antibiotic’s effectiveness against resistant strains.
Uses of Metformin, Ceftriaxone & Sulbactam for Injection 375MG
Respiratory Tract Infections: Including pneumonia, bronchitis, and lung abscesses.
Urinary Tract Infections (UTIs): Complicated or resistant infections of the bladder or kidneys.
Meningitis: Serious infections of the brain and spinal cord membranes.
Skin and Soft Tissue Infections: Including infected wounds, abscesses, and cellulitis.
Bone and Joint Infections: Such as osteomyelitis.
Intra-abdominal Infections: Including peritonitis and stomach infections.
Surgical Prophylaxis: Given before surgery to prevent post-operative infections.
Other Serious Infections: Septicemia (blood infection), gonorrhea, and ear infections (otitis media)
Partner with Fortune Labs for PCD Franchise with Ceftriaxone & Sulbactam for Injection 375MG
Fortune Labs, with all the latest molecules and continuously progressing under the table guidance of our Managing Experts.
- We provide a wide range of formulations such as tablets, injections, and new drugs that are DCGI-approved.
- These include Analgesics, Antibiotics & Anti-Infectives, Anticolds & Anti Allergics, and Antipsychotic Drugs.
- Apart from these, our range also includes Cardiovascular Drugs, Gastro & Antiemetic & Anti Ulcerant, Haematirics, Hormones, Neurology Supplements, and Nutritional Supplements.
- Our entire range also encompasses Table Syrup, Protesachetschet, Dry Powder, Capsules, Injectables, Ointment, Eye & Ear / Nasal Drops, and Yurvedic Products.
- Manufactured as per WHO GMP norms, Quality is Own Prime Concern; these are assured to have high-quality standards. This firm is a sister concern of Prosperity Six Pharmaceuticals (ISO 9001:2008, WHO, GMP)
Some Common Side Effects of Ceftriaxone & Sulbactam for Injection 375MG
Injection Site Reactions: Pain, swelling, redness, tenderness, or a hard lump where the medicine was administered.
Gastrointestinal Issues: Diarrhea, nausea, vomiting, indigestion, or an upset stomach.
Skin Reactions: Rash, itching, or hives.
General Discomfort: Dizziness, headache, or excessive sweating.
Laboratory Alterations: Changes in white blood cell counts (increased eosinophils or decreased lymphocytes), low blood platelets, or transient elevations in liver enzymes.
Severe Allergic Reactions (Anaphylaxis): Difficulty breathing, swelling of the face, lips, tongue, or throat, and severe skin rashes.
Severe Diarrhea: Watery or bloody stools (which may indicate a Clostridium difficile infection), sometimes occurring weeks after treatment.
Neurological Problems: Confusion, memory loss, or seizures (more common in cases of overdose).
Blood or Organ Issues: Unusual bleeding or bruising, yellowing of the skin or eyes (jaundice), and dark urine.
Frequently Asked Questions
What is Ceftriaxone & Sulbactam for Injection 375 mg?
It is a combination antibiotic injection that includes Ceftriaxone, a third-generation cephalosporin antibiotic, and Sulbactam, a beta-lactamase inhibitor that enhances the effectiveness of Ceftriaxone against resistant bacteria.
How does this medicine work?
Ceftriaxone works by disrupting the bacterial cell wall synthesis, leading to bacterial death. Sulbactam inhibits beta-lactamase enzymes produced by certain bacteria, protecting Ceftriaxone from degradation and improving its antibacterial activity.
What infections does this injection treat?
It is indicated for the treatment of various bacterial infections, including respiratory, urinary tract, skin and soft tissue infections, intra-abdominal infections, and other serious bacterial illnesses.
How is the injection administered?
This product is intended for intravenous (IV) or intramuscular (IM) administration by a healthcare professional. Self-administration is not recommended.
What is the usual dosage?
Dosage and frequency are determined by the treating physician based on the type and severity of infection and patient factors; therefore, always follow medical guidance. (General dose information is outside the scope of over-the-counter product description; consult prescribing information.)
Can this medication be used in pregnancy and breastfeeding?
Use during pregnancy should be based on a physician’s assessment of benefits versus risks. Ceftriaxone is excreted in breast milk in low amounts, so caution is advised during breastfeeding.
What are the common side effects?
Common side effects may include pain or redness at the injection site, gastrointestinal disturbances such as diarrhea, nausea, and vomiting, elevated liver enzymes, rash, and changes in blood cell counts.
